{"product_id":"cdc42-antibody-cat-fnab01530","title":"CDC42 antibody , Cat. #  FNab01530","description":"\u003cp\u003e\u003cb\u003eSize\u003c\/b\u003e:100ug\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification\u003c\/b\u003e:Immunogen affinity purified\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurity\u003c\/b\u003e:?95% as determined by SDS-PAGE\u003c\/p\u003e\u003cp\u003e\u003cb\u003eHost\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone ID\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage\u003c\/b\u003e:PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze \/ thaw cycles.)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2\/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:cell division cycle 42 (GTP binding protein, 25kDa)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSynonyms\u003c\/b\u003e:CDC42Hs, G25K, TKS\u003c\/p\u003e\u003cp\u003e\u003cb\u003eObserved MW\u003c\/b\u003e:21 kDa\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniprot ID\u003c\/b\u003e:P60953\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReactivity\u003c\/b\u003e:Human, Mouse, Rat\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Application\u003c\/b\u003e:ELISA, WB, IHC, IF\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRecommended dilution\u003c\/b\u003e:WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200\u003c\/p\u003e\u003cp\u003e\u003cb\u003eGene ID\u003c\/b\u003e:998\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Area\u003c\/b\u003e:Immunology, Signal Transduction, Cell Division and Proliferation\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40499418726500,"sku":"FNab01530","price":386.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_49a6ca45-4edb-4d14-99b4-e508b6e3e8d8.jpg?v=1660499984","url":"https:\/\/www.genebiosystems.com\/en-fr\/products\/cdc42-antibody-cat-fnab01530","provider":"GeneBio ","version":"1.0","type":"link"}