{"product_id":"tnfsf10-antibody-cat-csb-pa272904","title":"TNFSF10 Antibody - Cat. #: CSB-PA272904","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:Apo 2 ligand antibody; APO 2L antibody; Apo-2 ligand antibody; Apo-2L antibody; APO2L antibody; CD253 antibody; CD253 antigen antibody; Chemokine tumor necrosis factor ligand superfamily member 10 antibody; Protein TRAIL antibody; TL2 antibody; TNF Related Apoptosis Inducing Ligand antibody; TNF related apoptosis inducing ligand TRAIL antibody; TNF-related apoptosis-inducing ligand antibody; TNF10_HUMAN antibody; TNFSF10 antibody; TRAIL antibody; Tumor necrosis factor (ligand) family member 10 antibody; Tumor Necrosis Factor (ligand) Superfamily Member 10 antibody; Tumor necrosis factor apoptosis inducing ligand splice variant delta antibody; Tumor necrosis factor ligand superfamily member 10 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:P50591\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Synthesized peptide derived from internal of Human CD253.\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB, IF; WB:1:500-1:3000, IF:1:100-1:500\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Cytokine that binds to TNFRSF10A\/TRAILR1, TNFRSF10B\/TRAILR2, TNFRSF10C\/TRAILR3, TNFRSF10D\/TRAILR4 and possibly also to TNFRSF11B\/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C\/TRAILR3, TNFRSF10D\/TRAILR4 and TNFRSF11B\/OPG that cannot induce apoptosis.\u003cbr\u003e\u003cbr\u003eWiley S.R., Immunity 3:673-682(1995).\u003cbr\u003ePitti R.M., J. Biol. Chem. 271:12687-12690(1996).\u003cbr\u003eHymowitz S.G., Mol. Cell 4:563-571(1999).\u003cbr\u003e\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:TNFSF10\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Cancer?Cardiovascular?Cell biology\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40483977265252,"sku":"CSB-PA272904","price":593.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_f1e37654-714b-4eb9-bdf6-0e267d44f2cc.jpg?v=1660085166","url":"https:\/\/www.genebiosystems.com\/en-de\/products\/tnfsf10-antibody-cat-csb-pa272904","provider":"GeneBio ","version":"1.0","type":"link"}