{"product_id":"taok3-antibody-cat-csb-pa935138","title":"TAOK3 Antibody - Cat. #: CSB-PA935138","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:CTCL tumor antigen HD CL 09 antibody; CTCL-associated antigen HD-CL-09 antibody; Cutaneous T cell lymphoma tumor antigen HD CL 09 antibody; Cutaneous T-cell lymphoma-associated antigen HD-CL-09 antibody; Dendritic cell derived protein kinase antibody; Dendritic cell-derived protein kinase antibody; DKFZp666H245 antibody; DPK antibody; FLJ31808 antibody; hKFC A antibody; hKFC-A antibody; JIK antibody; JNK\/SAPK inhibitory kinase antibody; JNK\/SAPK-inhibitory kinase antibody; Jun kinase inhibitory kinase antibody; Jun kinase-inhibitory kinase antibody; KDS antibody; Kinase from chicken homolog A antibody; MAP3K18 antibody; Serine kinase antibody; Serine\/threonine-protein kinase TAO3 antibody; STE20 like kinase antibody; TAO kinase 3 antibody; TAOK3 antibody; TAOK3_HUMAN antibody; Thousand and one amino acid protein 3 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q9H2K8\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Synthesized peptide derived from internal of Human TAOK3.\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB; WB:1:500-1:3000\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Serine\/threonine-protein kinase that acts as a regulator of the p38\/MAPK14 stress-activated MAPK cascade and of the MAPK8\/JNK cascade. Acts as an activator of the p38\/MAPK14 stress-activated MAPK cascade. In response to DNA damage, involved in the G2\/M transition DNA damage checkpoint by activating the p38\/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. Inhibits basal activity of MAPK8\/JNK cascade and diminishes its activation in response epidermal growth factor (EGF).\u003cbr\u003e\u003cbr\u003eTassi E., J. Biol. Chem. 274:33287-33295(1999).\u003cbr\u003eZhang W., Biochem. Biophys. Res. Commun. 274:872-879(2000).\u003cbr\u003eYustein J.T., Oncogene 22:6129-6141(2003).\u003cbr\u003e\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:TAOK3\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Epigenetics and Nuclear Signaling;Signal transduction\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40483766206564,"sku":"CSB-PA935138","price":593.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_0cd93e58-9eb3-4ea3-b5d6-a50f9a153ac5.jpg?v=1660075730","url":"https:\/\/www.genebiosystems.com\/en-de\/products\/taok3-antibody-cat-csb-pa935138","provider":"GeneBio ","version":"1.0","type":"link"}