SYNE4 Antibody, Biotin conjugated - Cat. #: CSB-PA847615LD01HU

SKU: CSB-PA847615LD01HU

Size :50ug

Clone Number:

Aliases:SYNE4 antibody; C19orf46 antibody; Nesprin-4 antibody; KASH domain-containing protein 4 antibody; KASH4 antibody; Nuclear envelope spectrin repeat protein 4 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q8N205

Immunogen:Recombinant Human Nesprin-4 protein (1-242AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Behaves as a kinesin cargo, providing a functional binding site for kinesin-1 at the nuclear envelope. Hence may contribute to the establishment of secretory epithelial morphology by promoting kinesin-dependent apical migration of the centrosome and Golgi apparatus and basal localization of the nucleus.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:SYNE4

Research Areas:Cell biology