SORL1 Antibody - Cat. #: CSB-PA821688LA01HU

SKU: CSB-PA821688LA01HU

Size :50ug

Clone Number:

Aliases:C11orf32 antibody; FLJ21930 antibody; FLJ39258 antibody; gp250 antibody; LDLR relative with 11 ligand binding repeats antibody; LDLR relative with 11 ligand-binding repeats antibody; Low density lipoprotein receptor relative with 11 ligand binding repeats antibody; Low-density lipoprotein receptor relative with 11 ligand-binding repeats antibody; LR 11 antibody; LR11 antibody; LRP 9 antibody; LRP9 antibody; Mosaic protein LR11 antibody; SORL 1 antibody; SORL_HUMAN antibody; SORL1 antibody; SorLA 1 antibody; SorLA antibody; SorLA-1 antibody; Sortilin related receptor antibody; Sortilin related receptor L(DLR class) A repeats containing antibody; Sortilin-related receptor antibody; Sorting protein related receptor containing LDLR class A repeats antibody; Sorting protein-related receptor containing LDLR class A repeats antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q92673

Immunogen:Recombinant Human Sortilin-related receptor protein (525-744AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:Likely to be a multifunctional endocytic receptor, that may be implicated in the uptake of lipoproteins and of proteases. Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. Binds the receptor-associated protein (RAP). Could play a role in cell-cell interaction. Involved in APP trafficking to and from the Golgi apparatus. It probably acts as a sorting receptor that protects APP from trafficking to late endosome and from processing into amyloid beta, thereby reducing the burden of amyloidogenic peptide formation. Involved in the regulation of smooth muscle cells migration, probably through PLAUR binding and decreased internalization.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:SORL1

Research Areas:Neuroscience; Metabolism; Signal transduction