{"product_id":"recombinant-peg10-monoclonal-antibody","title":"Recombinant PEG10 Monoclonal Antibody","description":"\u003cp\u003e\u003cb\u003eSize:\u003c\/b\u003e:50μL\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage\u003c\/b\u003e:Store at -20℃ Valid for 12 months. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eShipping\u003c\/b\u003e:Ice bag\u003c\/p\u003e\u003cp\u003e\u003cb\u003eExp date\u003c\/b\u003e:12 months\u003c\/p\u003e\u003cp\u003e\u003cb\u003eCategory ID_II\u003c\/b\u003e:Primary Antibodies\u003c\/p\u003e\u003cp\u003e\u003cb\u003eCategory ID_III\u003c\/b\u003e:Monoclonal Antibodies;Recombinant Antibodies\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAbbreviation\u003c\/b\u003e:PEG10\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Synonym\u003c\/b\u003e:PEG;RTL;Mart;RGAG;SIRH;KIAA;PEG10;EDR;HB-1;MEF3L;2-Mar;Mart2;RGAG3;RTL2;SIRH1;KIAA1051;MEF3L1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Epigenetics and Nuclear Signaling;Cancer;Stem Cells\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugation\u003c\/b\u003e:Unconjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eHost\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies reactivity\u003c\/b\u003e:Human;Rat;Mouse\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplication\u003c\/b\u003e:WB\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG,κ\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Monoclonal;Recombinant\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone NO.\u003c\/b\u003e:A675\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUNIProt ID\u003c\/b\u003e:Q86TG7\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAccession\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Paternally expressed gene 10(PEG10 ) is an imprinted gene which is derived from a Ty3\/Gypsy long terminal repeat (LTR) retrotransposon family encoding Gag- and Pol-like domains. Deletion of PEG10 in mice leads to embryonic lethality due to defects in placental formation. PEG10 is aberrantly expressed in several cancer types, including hepatocellular carcinoma, and contributes to tumorigenesis by affecting cell proliferation, apoptosis, and metastasis. The PEG10 gene has two overlapping open reading frames that are regulated by the programmed process of -1 frameshifting. The first encoded protein ORF1 (or RF1) has a Gag domain with coiled-coil domain and zinc finger domains, while ORF1-2 (or RF1\/RF2) is produced by -1 frameshifting and creates a fusion of the ORF1 Gag domain with a carboxyl-terminal Pol-like protease domain. PEG10 has retained the ability to form virus-like particles (VLPs) that are secreted as small extracellular vesicles delivered to distant sites.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConcentration\u003c\/b\u003e:1 mg\/mL\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Recombinant human PEG10 fragment\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification method\u003c\/b\u003e:Protein A purified\u003c\/p\u003e\u003cp\u003e\u003cb\u003eDilution\u003c\/b\u003e:WB 1:500-1:1000\u003c\/p\u003e\u003cp\u003e\u003cb\u003eCalculated MW\u003c\/b\u003e:55\/100 kDa\u003c\/p\u003e\u003cp\u003e\u003cb\u003eObservedMW\u003c\/b\u003e:55\/100 kDa\u003c\/p\u003e","brand":"GeneBio Systems","offers":[{"title":"Default Title","offer_id":48644790845540,"sku":"AN301959L","price":349.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/files\/no_image_default_image-jpeg_83231b12-5c61-401a-859f-d4f808fdc3b7.jpg?v=1782654484","url":"https:\/\/www.genebiosystems.com\/en-de\/products\/recombinant-peg10-monoclonal-antibody","provider":"GeneBio ","version":"1.0","type":"link"}