{"product_id":"rchy1-antibody-cat-csb-pa822281esr1hu","title":"RCHY1 Antibody - Cat. #: CSB-PA822281ESR1HU","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:Androgen receptor N terminal interacting protein antibody; Androgen receptor N-terminal-interacting protein antibody; ARNIP antibody; CH-rich-interacting match with PLAG1 antibody; CHIMP antibody; E3 ubiquitin-protein ligase Pirh2 antibody; hARNIP antibody; hPirh2 antibody; p53 induced protein with a RING H2 domain antibody; p53-induced RING-H2 protein antibody; PIRH2E antibody; PIRH2F antibody; PRO1996 antibody; RCHY1 antibody; Ring finger and CHY zinc finger domain containing 1 E3 ubiquitin protein ligase antibody; RING finger and CHY zinc finger domain-containing protein 1 antibody; RING finger protein 199 antibody; RNF199 antibody; ZCHY antibody; ZFP 363 antibody; zinc finger CHY type antibody; Zinc finger protein 363 antibody; ZN363_HUMAN antibody; ZNF363 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q96PM5\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Recombinant Human RING finger and CHY zinc finger domain-containing protein 1 protein (1-261AA)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53\/TP53, P73, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53\/TP53. Monoubiquitinates the translesion DNA polymerase POLH. Contributes to the regulation of the cell cycle progression. Increases AR transcription factor activity.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antigen Affinity Purified\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:RCHY1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Cancer; Cell biology\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40486234456164,"sku":"CSB-PA822281ESR1HU","price":331.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_548e35f9-7f48-4b9a-8381-dfb7d00d4da0.jpg?v=1660143272","url":"https:\/\/www.genebiosystems.com\/en-de\/products\/rchy1-antibody-cat-csb-pa822281esr1hu","provider":"GeneBio ","version":"1.0","type":"link"}