{"product_id":"pparg-antibody-cat-csb-pa216430","title":"PPARG Antibody - Cat. #: CSB-PA216430","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:CIMT1 antibody; GLM1 antibody; NR1C3 antibody; Nuclear receptor subfamily 1 group C member 3 antibody; OTTHUMP00000185032 antibody; OTTHUMP00000185036 antibody; Peroxisome proliferator activated nuclear receptor gamma variant 1 antibody; Peroxisome proliferator activated receptor gamma 1 antibody; Peroxisome Proliferator Activated Receptor gamma antibody; Peroxisome proliferator-activated receptor gamma antibody; PPAR gamma antibody; PPAR-gamma antibody; PPARG antibody; PPARG_HUMAN antibody; PPARG1 antibody; PPARG2 antibody; PPARgamma antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:P37231\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Peptide sequence around aa.50~54 (L-S-V-M-E) derived from Human PPARg\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human, Mouse\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB; WB:1:500-1:1000\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. Identification, characterization, and tissue distribution of human peroxisome proliferator-activated receptor (PPAR) isoforms PPARgamma2 versus PPARgamma1 and activation with retinoid X receptor agonists and antagonists.\"\u003cbr\u003e\u003cbr\u003eMukherjee R., Jow L., Croston G.E., et al. J. Biol. Chem. 272:8071-8076(1997) \"Cloning and characterization of RAP250, a nuclear receptor coactivator.\"\u003cbr\u003eCaira F., Antonson P., Pelto-Huikko M., et al. J. Biol. Chem. 275:5308-5317(2000) \"Identification of protein arginine methyltransferase 2 as a coactivator for estrogen receptor a.\"\u003cbr\u003eQi C., Chang J., Zhu Y.,et al. J. Biol. Chem. 277:28624-28630(2002) \"\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Supplied at 1.0mg\/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:PPARG\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Epigenetics and Nuclear Signaling?Neuroscience;Cardiovascular;Metabolism;Stem cells\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40483690348644,"sku":"CSB-PA216430","price":593.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_4b06580d-df82-4db7-a8c5-e368415a93c4.jpg?v=1660073943","url":"https:\/\/www.genebiosystems.com\/en-de\/products\/pparg-antibody-cat-csb-pa216430","provider":"GeneBio ","version":"1.0","type":"link"}