{"product_id":"phospho-src-tyr529-antibody-cat-csb-pa954497","title":"Phospho-SRC (Tyr529) Antibody - Cat. #: CSB-PA954497","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:ASV antibody; Avian sarcoma virus antibody; AW259666 antibody; c SRC antibody; CDNA FLJ14219 fis clone NT2RP3003800 highly similar to Rattus norvegicus tyrosine protein kinase pp60 c src mRNA antibody; cSrc antibody; EC 2.7.10.2 antibody; Neuronal CSRC tyrosine specific protein kinase antibody; Neuronal proto-oncogene tyrosine-protein kinase Src antibody; Neuronal SRC antibody; Oncogene SRC antibody; OTTHUMP00000174476 antibody; OTTHUMP00000174477 antibody; p60 Src antibody; p60-Src antibody; p60c-src antibody; p60Src antibody; pp60c src antibody; pp60c-src antibody; pp60csrc antibody; Proto oncogene tyrosine protein kinase Src antibody; Proto-oncogene c-Src antibody; Proto-oncogene tyrosine-protein kinase Src antibody; Protooncogene SRC antibody; Protooncogene SRC Rous sarcoma antibody; Src antibody; SRC Oncogene antibody; SRC proto oncogene non receptor tyrosine kinase antibody; SRC_HUMAN antibody; SRC1 antibody; Tyrosine kinase pp60c src antibody; Tyrosine protein kinase SRC 1 antibody; Tyrosine protein kinase SRC1 antibody; v src avian sarcoma (Schmidt Ruppin A2) viral oncogene homolog antibody; V src sarcoma (Schmidt Ruppin A 2) viral oncogene homolog (avian) antibody; v src sarcoma (Schmidt Ruppin A 2) viral oncogene homolog avian antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:P12931\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Peptide sequence around phosphorylation site of tyrosine 529 (P-Q-Y(p)-Q-P) derived from Human Src.\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human, Mouse, Rat\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB, IHC, IF; WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003eproto-oncogenic cytoplasmic tyrosine kinase of the SRC family. Highly expressed in certain fully differentiated cells such as neurons, platelets and macrophages. Phosphorylation of an activation loop tyrosine activates the enzyme; phosphorylation of a tyrosine in the C-terminus by Csk inhibits the enzyme. \u003cbr\u003e\u003cbr\u003ePyper J.M., (1985) Mol. Cell. Biol. 5:831-838 \u003cbr\u003ePyper J.M.(1990) Mol. Cell. Biol. 10:2035-2040 \u003cbr\u003eXu W., (1997).Nature 385:595-602 \u003cbr\u003eBenes C.H., (2005) Cell 121:271-280\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Supplied at 1.0mg\/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:SRC\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Epigenetics and Nuclear Signaling;Cancer;Signal transduction\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40484053844068,"sku":"CSB-PA954497","price":719.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_37194e28-1873-47ce-9eb2-6ed4115481c4.jpg?v=1660087121","url":"https:\/\/www.genebiosystems.com\/en-de\/products\/phospho-src-tyr529-antibody-cat-csb-pa954497","provider":"GeneBio ","version":"1.0","type":"link"}