{"product_id":"phospho-gata1-ser142-antibody-cat-csb-pa592144","title":"Phospho-GATA1 (Ser142) Antibody - Cat. #: CSB-PA592144","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:Anemia; X-linked; without thrombocytopenia; included antibody; ERYF 1 antibody; Eryf1 antibody; Erythroid transcription factor antibody; Erythrold transcription factor 1 antibody; GATA 1 antibody; GATA binding factor 1 antibody; GATA binding protein 1 (globin transcription factor 1) antibody; GATA binding protein 1 antibody; GATA-1 antibody; GATA-binding factor 1 antibody; GATA1 antibody; GATA1_HUMAN antibody; GF 1 antibody; GF-1 antibody; GF1 antibody; Globin transcription factor 1 antibody; NF E1 antibody; NF E1 DNA binding protein antibody; NF-E1 DNA-binding protein antibody; NFE 1 antibody; NFE1  antibody; Nuclear factor erythroid 1 antibody; Transcription factor GATA1 antibody; XLANP antibody; XLTDA antibody; XLTT antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:P15976\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Peptide sequence around phosphorylation site of serine 142 (R-L-S(p)-P-D) derived from Human GATA1.\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human, Mouse, Rat\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB, IHC, IF; WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003eGATA1 encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia. \u003cbr\u003e\u003cbr\u003eZon LI, et al. (1990) Proc Natl Acad. Sci USA. 87: 668-672. \u003cbr\u003eTrainor C D, et al. (1990) Nature. 343: 92-96. \u003cbr\u003eNichols K E, et al. (2000) Nat Genet. 24: 266-270.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Supplied at 1.0mg\/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:GATA1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Epigenetics and Nuclear Signaling;Developmental biology;Stem cells\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40484048863332,"sku":"CSB-PA592144","price":724.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_e5fe7bca-94c7-4828-8bff-aea501279309.jpg?v=1660086970","url":"https:\/\/www.genebiosystems.com\/en-de\/products\/phospho-gata1-ser142-antibody-cat-csb-pa592144","provider":"GeneBio ","version":"1.0","type":"link"}