{"product_id":"nmnat1-antibody-cat-csb-pa864012esr2hu","title":"NMNAT1 Antibody - Cat. #: CSB-PA864012ESR2HU","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:EC 2.7.7.1 antibody; LCA9 antibody; Leber's congenital amaurosis 9 antibody; NaMN adenylyltransferase 1 antibody; nicotinamide nucleotide adenylyltransferase 1 antibody; Nicotinamide-nucleotide adenylyltransferase 1 antibody; Nicotinamide\/nicotinic acid mononucleotide adenylyltransferase 1 antibody; nicotinate nucleotide adenylyltransferase 1 antibody; Nicotinate-nucleotide adenylyltransferase 1 antibody; NMN adenylyltransferase 1 antibody; NMN\/NaMN adenylyltransferase 1 antibody; NMNA1_HUMAN antibody; Nmnat 1 antibody; Nmnat1 antibody; OTTHUMP00000001731 antibody; OTTHUMP00000001732 antibody; OTTHUMP00000035892 antibody; PNAT 1 antibody; PNAT1 antibody; pyridine nucleotide adenylyltransferase 1 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q9HAN9\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Recombinant Human Nicotinamide\/nicotinic acid mononucleotide adenylyltransferase 1 protein (1-279AA)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, prefers NAD(+) and NaAD as substrates and degrades NADH, nicotinic acid adenine dinucleotide phosphate (NHD) and nicotinamide guanine dinucleotide (NGD) less effectively. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NaADP(+). Protects against axonal degeneration following mechanical or toxic insults.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antigen Affinity Purified\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:NMNAT1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Epigenetics and Nuclear Signaling; Neuroscience; Cancer; Metabolism; Signal transduction\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40486142214244,"sku":"CSB-PA864012ESR2HU","price":331.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_74c933c4-b633-4c90-b7cc-131bf1c1db5d.jpg?v=1660141380","url":"https:\/\/www.genebiosystems.com\/en-de\/products\/nmnat1-antibody-cat-csb-pa864012esr2hu","provider":"GeneBio ","version":"1.0","type":"link"}