{"product_id":"kdm2b-antibody-cat-csb-pa836777la01hu","title":"KDM2B Antibody - Cat. #: CSB-PA836777LA01HU","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ug\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:[Histone-H3]-lysine-36 demethylase 1B antibody; CXXC-type zinc finger protein 2 antibody; CXXC2 antibody; F box and leucine rich repeat protein 10 antibody; F box protein FBL10 antibody; F-box and leucine-rich repeat protein 10 antibody; F-box protein FBL10 antibody; F-box\/LRR-repeat protein 10 antibody; Fbl10 antibody; FBXL10 antibody; JEMMA (Jumonji domain EMSY interactor methyltransferase motif) protein antibody; JHDM1B antibody; JmjC domain-containing histone demethylation protein 1B antibody; Jumonji C domain containing histone demethylase 1B antibody; Jumonji domain-containing EMSY-interactor methyltransferase motif protein antibody; kdm2b antibody; KDM2B_HUMAN antibody; Lysine (K) specific demethylase 2B antibody; Lysine-specific demethylase 2B antibody; PCCX2 antibody; Protein containing CXXC domain 2 antibody; Protein JEMMA antibody; Protein-containing CXXC domain 2 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q8NHM5\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Recombinant Human Lysine-specific demethylase 2B protein (1274-1336AA)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, IF; Recommended dilution: IF:1:50-1:200\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Histone demethylase that demethylates \\'Lys-4\\' and \\'Lys-36\\' of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 \\'Lys-4\\' and dimethylated H3 \\'Lys-36\\' residue while it has weak or no activity for mono- and tri-methylated H3 \\'Lys-36\\'. Preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation. May also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:\u0026gt;95%, Protein G purified\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Preservative: 0.03% Proclin 300\u003cbr\u003eConstituents: 50% Glycerol, 0.01M PBS, pH 7.4\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:KDM2B\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Epigenetics and Nuclear Signaling\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40487133413476,"sku":"CSB-PA836777LA01HU","price":332.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_5f04dd97-c206-497f-92fd-dbd59bcf1108.jpg?v=1660159553","url":"https:\/\/www.genebiosystems.com\/en-de\/products\/kdm2b-antibody-cat-csb-pa836777la01hu","provider":"GeneBio ","version":"1.0","type":"link"}