{"product_id":"gzmb-antibody-cat-csb-pa010082la01hu","title":"GZMB Antibody - Cat. #: CSB-PA010082LA01HU","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ug\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:C11 antibody; Cathepsin G like 1 antibody; Cathepsin G-like 1 antibody; CCPI antibody; CGL 1 antibody; CGL1 antibody; CSP B antibody; CSPB antibody; CTLA 1 antibody; CTLA-1 antibody; CTLA1 antibody; CTSGL1 antibody; Cytotoxic serine protease B antibody; Cytotoxic T lymphocyte associated serine esterase 1 antibody; Cytotoxic T lymphocyte proteinase 2 antibody; Cytotoxic T-lymphocyte proteinase 2 antibody; Fragmentin 2 antibody; Fragmentin-2 antibody; GRAB_HUMAN antibody; Granzyme 2 antibody; Granzyme B (granzyme 2; cytotoxic T lymphocyte associated serine esterase 1) antibody; Granzyme B antibody; Granzyme-2 antibody; GranzymeB antibody; GRB antibody; Gzmb antibody; Hlp antibody; Human lymphocyte protein antibody; Lymphocyte protease antibody; Protease; serine; B antibody; SECT antibody; T cell serine protease 1 3E antibody; T cell serine protease 1-3E antibody; T-cell serine protease 1-3E antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:P10144\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Recombinant Human Granzyme B protein (21-247AA)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, IHC, IF; Recommended dilution: IHC:1:500-1:1000, IF:1:200-1:500\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:\u0026gt;95%, Protein G purified\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Preservative: 0.03% Proclin 300\u003cbr\u003eConstituents: 50% Glycerol, 0.01M PBS, PH 7.4\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:GZMB\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Cell biology; Immunology\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40484206936164,"sku":"CSB-PA010082LA01HU","price":332.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_5e8a292c-9532-4a87-a104-71e8398582aa.jpg?v=1660091213","url":"https:\/\/www.genebiosystems.com\/en-de\/products\/gzmb-antibody-cat-csb-pa010082la01hu","provider":"GeneBio ","version":"1.0","type":"link"}