{"product_id":"bcl2l12-antibody-cat-csb-pa995732","title":"BCL2L12 Antibody - Cat. #: CSB-PA995732","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:B2L12_HUMAN antibody; BCL 2 like 12 (proline rich) antibody; BCL 2 like 12 antibody; BCL 2 like 12 isoform 1 antibody; Bcl 2 like 12 protein antibody; Bcl 2 related proline rich protein antibody; Bcl-2-like protein 12 antibody; Bcl-2-related proline-rich protein antibody; BCL2 like 12 (proline rich) antibody; BCL2 like 12 antibody; BCL2 like 12 isoform 1 antibody; Bcl2 like 12 protein antibody; Bcl2 related proline rich protein antibody; Bcl2-L-12 antibody; BCL2L12 antibody; BPR antibody; MGC120313 antibody; MGC120314 antibody; MGC120315 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q9HB09\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Synthesized peptide derived from internal of Human BCL2L12.\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human, Mouse\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB; WB:1:500-1:3000\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants.\u003cbr\u003e\u003cbr\u003eScorilas A., Genomics 72:217-221(2001) [PubMed: 11401436].\u003cbr\u003eHillman R.T., Genome Biol. 5:R8.1-R8.16(2004) [PubMed: 14759258].\u003cbr\u003eOlsen J.V., Cell 127:635-648(2006) [PubMed: 17081983].\u003cbr\u003e\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:BCL2L12\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Cancer;Cell biology;Metabolism\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40483732226148,"sku":"CSB-PA995732","price":589.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_9b6c382c-c3d0-4ecf-aca9-8ba34f44ec13.jpg?v=1660074926","url":"https:\/\/www.genebiosystems.com\/en-de\/products\/bcl2l12-antibody-cat-csb-pa995732","provider":"GeneBio ","version":"1.0","type":"link"}