{"product_id":"ar-polyclonal-antibody","title":"AR Polyclonal Antibody","description":"\u003cp\u003e\u003cb\u003eSize:\u003c\/b\u003e:120μL\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage\u003c\/b\u003e:Store at -20℃ Valid for 12 months. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eShipping\u003c\/b\u003e:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eExp date\u003c\/b\u003e:12 months\u003c\/p\u003e\u003cp\u003e\u003cb\u003eCategory ID_II\u003c\/b\u003e:Primary Antibodies\u003c\/p\u003e\u003cp\u003e\u003cb\u003eCategory ID_III\u003c\/b\u003e:Polyclonal Antibodies\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAbbreviation\u003c\/b\u003e:AR\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Synonym\u003c\/b\u003e:AIS;ANDR;Androgen nuclear receptor variant 2;Androgen receptor (dihydrotestosterone receptor;testicular feminization;spinal and bulbar muscular atrophy;Kennedy disease);Androgen receptor;androgen receptor splice variant 4b;AR;AR8;DHTR;Dihydro testosterone receptor;Dihydrotestosterone receptor (DHTR);Dihydrotestosterone receptor;HUMARA;HYSP1;KD;Kennedy disease (KD);NR3C4;Nuclear receptor subfamily 3 group C member 4 (NR3C4);Nuclear receptor subfamily 3 group C member 4;SBMA;SMAX1;Spinal and bulbar muscular atrophy (SBMA);Spinal and bulbar muscular atrophy;Testicular Feminization (TFM);TFM\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Cancer;Epigenetics and Nuclear Signaling;Developmental Biology;Signal Transduction\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugation\u003c\/b\u003e:Unconjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eHost\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies reactivity\u003c\/b\u003e:Human;Mouse;Rat\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplication\u003c\/b\u003e:IHC\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone NO.\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUNIProt ID\u003c\/b\u003e:P10275;P19091;P15207\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAccession\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConcentration\u003c\/b\u003e:0.83 mg\/mL\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:KLH conjugated Synthetic peptide corresponding to Mouse Androgen receptor\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification method\u003c\/b\u003e:Affinity purification\u003c\/p\u003e\u003cp\u003e\u003cb\u003eDilution\u003c\/b\u003e:IHC 1:300-1:1000\u003c\/p\u003e\u003cp\u003e\u003cb\u003eCalculated MW\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eObservedMW\u003c\/b\u003e:\u003c\/p\u003e","brand":"GeneBio Systems","offers":[{"title":"Default Title","offer_id":48644653744228,"sku":"E-AB-70112","price":364.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/files\/no_image_default_image-jpeg_261e5452-a1fc-427b-88a9-05d6726e350e.jpg?v=1782650265","url":"https:\/\/www.genebiosystems.com\/en-de\/products\/ar-polyclonal-antibody","provider":"GeneBio ","version":"1.0","type":"link"}