{"title":"SkinnyTube™ 10X Dx™","description":"SkinnyTube™ 10X Dx™ tube is to replace the conventional transport medium tube for swab sample collection. By having the SkinnyTube\u003cspan data-mce-fragment=\"1\"\u003e™\u003c\/span\u003e structure, the novel tube can stabilize  collected swab samples with much less volume of medium, dramatically raising the concentration of collected sample, at the same time  still protecting the swab sample with medium stabilization 100% of time during sample transportation from collection to lab testing sites.","products":[{"product_id":"skinnytube-10x-dx-viral-transport-medium-tubes-and-swab-kit","title":"SkinnyTube™ 10X Dx™ Viral Transport Medium Tubes and Swab Kit-0.6 mL Fill","description":"\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cem data-mce-fragment=\"1\"\u003eSkinnyTube\u003c\/em\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003cspan data-contrast=\"auto\" data-mce-fragment=\"1\"\u003e™ \u003cstrong\u003e10X Dx™\u003c\/strong\u003e Viral Transport Medium System is designed for the collection and transport of clinical specimen for the preservation and recovery of viral agents and bacterial and other pathogens for diagnostic testing, with a gain of around 10 times concentration of collected swab samples, relative to the traditional transport medium tube.\u003c\/span\u003e\u003cspan data-ccp-props='{\"335551550\":6,\"335551620\":6}' data-mce-fragment=\"1\"\u003e \u003c\/span\u003e\u003cspan data-contrast=\"auto\" data-mce-fragment=\"1\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eThe internal compartment results in around 10X increased diagnostic sensitivity (10X Dx™) \u003c\/span\u003e\u003cspan data-contrast=\"auto\" data-mce-fragment=\"1\"\u003eby reducing sample dilution while introducing a secondary self-containment system to ensure maximum leakage prevention and safe transport. \u003c\/span\u003e\u003cspan data-ccp-props='{\"335551550\":6,\"335551620\":6}' data-mce-fragment=\"1\"\u003e This product is filled with 0.6 ml of medium, which when compared with  a conventional transport medium tube filled with 3 ml of medium results a 5 fold increase in concentration of the collected sample. Other \u003cem data-mce-fragment=\"1\"\u003eSkinnyTube\u003c\/em\u003e™ 10X Dx™ products with different fill volumes ranging from 0.2-0.5 ml can result in 5-15 X gain in concentration (compared to a conventional fill volume of 3 ml in a conventional tube). \u003c\/span\u003e\u003c\/p\u003e\n\u003cspan data-mce-fragment=\"1\"\u003e \u003c\/span\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eT\u003c\/span\u003e\u003cspan data-ccp-parastyle=\"Normal (Web)\" data-mce-fragment=\"1\"\u003ehe ready-to-use system combines \u003c\/span\u003e\u003cspan data-ccp-parastyle=\"Normal (Web)\" data-mce-fragment=\"1\"\u003ea\u003c\/span\u003e\u003cspan data-ccp-parastyle=\"Normal (Web)\" data-mce-fragment=\"1\"\u003e disposable \u003c\/span\u003e\u003cspan style=\"font-size: 0.875rem;\" data-contrast=\"auto\" data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cem data-mce-fragment=\"1\"\u003eSkinnyTube\u003c\/em\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003cspan style=\"font-size: 0.875rem;\" data-contrast=\"auto\" data-mce-fragment=\"1\"\u003e™ transport tube filled with non-inactivating viral transport medium (VTM) and a Puritan® PurFlock Ultra® Flocked Sterile nasal swab for efficient collection and safe transport. Each kit contains 1 SkinnyTube™ 5X Dx™ screw-cap cylindrical contour tube filled with 0.6 ml VTM and 1 Puritan® PurFlock Ultra® Sterile Flocked Nasal Swab. The VTM is stable from 2\u003c\/span\u003e\u003cspan style=\"font-size: 0.875rem;\" data-contrast=\"none\" data-mce-fragment=\"1\"\u003e°C to 4\u003c\/span\u003e\u003cspan style=\"font-size: 0.875rem;\" data-contrast=\"none\" data-mce-fragment=\"1\"\u003e°C with a neutral pH maintained by a buffer solution comprised of antimicrobial agents in addition to sources of protein and sucrose to support virus preservation for up to 48 hours. \u003c\/span\u003e\u003cspan style=\"font-size: 0.875rem;\" data-ccp-props='{\"134233117\":true,\"134233118\":true,\"335551550\":6,\"335551620\":6}' data-mce-fragment=\"1\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eThe non-inactivating viral transport medium included in these products is a universal transport medium formulated for virus preservation (Table 1). The key ingredients include:   \u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cem data-mce-fragment=\"1\"\u003eTable 1: Transport Medium Composition\u003c\/em\u003e \u003c\/p\u003e\n\u003ctable width=\"0\" data-mce-fragment=\"1\"\u003e\n\u003ctbody data-mce-fragment=\"1\"\u003e\n\u003ctr data-mce-fragment=\"1\"\u003e\n\u003ctd width=\"233\" data-mce-fragment=\"1\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eHank’s Balanced Salts \u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"233\" data-mce-fragment=\"1\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eL-Glutamic Acid \u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\"\u003e\n\u003ctd width=\"233\" data-mce-fragment=\"1\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eBovine Serum Albumin \u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"233\" data-mce-fragment=\"1\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003ePhenol Red \u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\"\u003e\n\u003ctd width=\"233\" data-mce-fragment=\"1\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eGelatin \u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"233\" data-mce-fragment=\"1\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eColistin \u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\"\u003e\n\u003ctd width=\"233\" data-mce-fragment=\"1\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eSucrose \u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"233\" data-mce-fragment=\"1\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eAmphotericin B \u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\"\u003e\n\u003ctd width=\"233\" data-mce-fragment=\"1\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eL-Cysteine \u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"233\" data-mce-fragment=\"1\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eVancomycin \u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\"\u003e\n\u003ctd width=\"233\" data-mce-fragment=\"1\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eHEPES \u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd width=\"233\" data-mce-fragment=\"1\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003epH: 7.3 ± 0.2 \u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp data-mce-fragment=\"1\"\u003e \u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-contrast=\"none\" data-mce-fragment=\"1\"\u003ePROCEDURE \u003c\/span\u003e\u003cspan data-contrast=\"auto\" data-mce-fragment=\"1\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003col data-mce-fragment=\"1\"\u003e\n\u003cli data-mce-fragment=\"1\"\u003e\n\u003cspan data-contrast=\"auto\" data-mce-fragment=\"1\"\u003e Open package containing the Puritan® swab and SkinnyTube™ tube filled with VTM.\u003c\/span\u003e\u003cspan data-ccp-props='{\"335551550\":6,\"335551620\":6}' data-mce-fragment=\"1\"\u003e\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003e\n\u003cspan data-contrast=\"auto\" data-mce-fragment=\"1\"\u003e Open the sterile swab pouch and collect the specimen without bending the nasal swab as directed by Puritan®. \u003c\/span\u003e\u003cspan data-ccp-props='{\"335551550\":6,\"335551620\":6}' data-mce-fragment=\"1\"\u003e\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003e\n\u003cspan data-contrast=\"auto\" data-mce-fragment=\"1\"\u003e Unscrew the tube’s cap aseptically and insert swab containing the sample into the media in the inner compartment without touching any other surfaces to prevent contamination.\u003c\/span\u003e\u003cspan data-ccp-props='{\"335551550\":6,\"335551620\":6}' data-mce-fragment=\"1\"\u003e\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003e\n\u003cspan data-contrast=\"auto\" data-mce-fragment=\"1\"\u003e Snap swab at the breakpoint highlighted by the black line using the edge of the tube and appropriately discard of the upper portion of the used swab into a medical waste container. \u003c\/span\u003e\u003cspan data-ccp-props='{\"335551550\":6,\"335551620\":6}' data-mce-fragment=\"1\"\u003e\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003e\n\u003cspan data-contrast=\"auto\" data-mce-fragment=\"1\"\u003e Align and lower the plunger with the opening of the inner compartment to seal off the medium tube and screw the cap back on to properly seal the tube. \u003c\/span\u003e\u003cspan data-ccp-props='{\"335551550\":6,\"335551620\":6}' data-mce-fragment=\"1\"\u003e\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003e\n\u003cspan data-contrast=\"auto\" data-mce-fragment=\"1\"\u003e Label the tube containing the specimen using appropriate identifications. \u003c\/span\u003e\u003cspan data-ccp-props='{\"335551550\":6,\"335551620\":6}' data-mce-fragment=\"1\"\u003e\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003e\n\u003cspan data-contrast=\"auto\" data-mce-fragment=\"1\"\u003e Follow local institutional procedures and send the SkinnyTube™ tube sample to the laboratory for analysis. \u003c\/span\u003e\u003cspan data-ccp-props='{\"335551550\":6,\"335551620\":6}' data-mce-fragment=\"1\"\u003e\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e \u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eSPECIFICATIONS\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eDesigned for compatibility with the Puritan® PurFlock Ultra® Sterile Flocked Nasal Swab with a break point at 30 mm.  \u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eDimensions:    Tube: 9.0 cm (height) by 5.5 cm (circumference) \u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eSwab: 153.4 mm handle (length) with 3.429 mm tip (diameter).\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eMaterials:       Tube: Polypropylene tube, silicone inner cap, and high-density polyethylene plastic (HDPE) cap (red) \u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eSwab: Polystyrene handle and flocked polyester tip. \u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e \u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003ePERFORMANCE CHARACTERISTICS\u003c\/strong\u003e\u003c\/span\u003e\u003cspan data-ccp-props='{\"201341983\":0,\"335559740\":259}' data-mce-fragment=\"1\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-contrast=\"auto\" data-mce-fragment=\"1\"\u003eTo investigate on the notion of raised analyte concentration in the novel tube compared to that of the conventional tube, the SkinnyTube™ with 0.3 ml of Hanks-balanced salt-based medium was compared to the conventional tube with 3 ml of Hanks-balanced salt based medium. \u003c\/span\u003e\u003cspan data-ccp-props='{\"201341983\":0,\"335559740\":259}' data-mce-fragment=\"1\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-contrast=\"auto\" data-mce-fragment=\"1\"\u003eA total of 36 swabs were tested. Each of the 36 swabs was dipped into a spiked mock sample containing a SARS-CoV-2 RNA (COVID-19 viral RNA). Then each of 18 dipped swabs was placed into a separate SkinnyTube™ (novel tube); each of the other 18 swabs were placed into a separate conventional tube. 100uL of the transport medium from each of the 36 tubes was removed, heated, and then tested in a duplex SARS-CoV-2 quantitative reverse transcription polymerase chain reaction (RT-qPCR). \u003c\/span\u003e\u003cspan data-ccp-props='{\"201341983\":0,\"335559740\":259}' data-mce-fragment=\"1\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-contrast=\"auto\" data-mce-fragment=\"1\"\u003eA duplex SARS-CoV-2 RT-qPCR tested 2 regions (N1 and N2 regions of the N gene) of the viral SARS-CoV-2 RNA to further validate the assay results. The cycle threshold (Ct) values from the RT-qPCR are listed below in Figure 1. The results showed that the average Ct value for N1 Region for the novel tube was 29.6 or was 3.1 less than that for the conventional tube (average Ct 32.7). Since Ct is a direct reflection of the analyte concentration, this difference corresponds to 8.5-fold more viral RNA analyte concentration in the novel tube than that for the conventional tube. The difference of average Ct value for N2 Region between the two groups of tubes was 4.7 (average Ct 35.5-30.9), corresponding to 25-fold viral RNA analyte concentration in the novel tube than that for the conventional tube. This \u0026gt; 10-fold increase in the viral RNA analyte concentration for N2 test was probably because when the assay result was near 37, the errors in Ct were inherently greater. \u003c\/span\u003e\u003cspan data-ccp-props='{\"201341983\":0,\"335559740\":259}' data-mce-fragment=\"1\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-contrast=\"auto\" data-mce-fragment=\"1\"\u003eThe N2 Region assay data showed that 5 of 18 (28%) samples were not even detectable (Ct\u0026lt;45 or 43 as criterion) in the conventional tube group, whereas all 18 samples in the novel tubes were detected. This suggests that the novel tubes are particularly more useful in the detection of low concentration (low positives near cut-off of an assay) samples .\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e For more information, please visit: \u003cstrong\u003e\u003ca title=\"skinnytube.ca\" href=\"http:\/\/www.skinnytube.ca\"\u003eskinnytube.ca\u003c\/a\u003e For research use only. \u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e \u003c\/p\u003e","brand":"GeneBio Systems","offers":[{"title":"50 Kits","offer_id":42350585741412,"sku":"SKT-031A -01","price":301.8,"currency_code":"CAD","in_stock":true},{"title":"300 Kits","offer_id":42350585774180,"sku":"SKT-031A -02","price":1632.96,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/files\/skinnytubekitimage.png?v=1698955132"},{"product_id":"copy-of-skinnytube-10x-dx-viral-transport-medium-tubes-and-swab-kit","title":"SkinnyTube™ 10X Dx™ Viral Transport Medium Tubes and Swab Kit-0.3 ml Fill","description":"\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cem data-mce-fragment=\"1\"\u003eSkinnyTube\u003c\/em\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\" data-contrast=\"auto\"\u003e™ \u003cstrong\u003e10X Dx™\u003c\/strong\u003e Viral Transport Medium System is designed for the collection and transport of clinical specimen for the preservation and recovery of viral agents and bacterial and other pathogens for diagnostic testing, with a gain of around 10 times concentration of collected swab samples, relative to the traditional transport medium tube.\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\" data-ccp-props='{\"335551550\":6,\"335551620\":6}'\u003e \u003c\/span\u003e\u003cspan data-mce-fragment=\"1\" data-contrast=\"auto\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eThe internal compartment results in around 10X increased diagnostic sensitivity (10X Dx™) \u003c\/span\u003e\u003cspan data-mce-fragment=\"1\" data-contrast=\"auto\"\u003eby reducing sample dilution while introducing a secondary self-containment system to ensure maximum leakage prevention and safe transport. \u003c\/span\u003e\u003cspan data-mce-fragment=\"1\" data-ccp-props='{\"335551550\":6,\"335551620\":6}'\u003e This product is filled with 0.3 ml of medium, which when compared with  a conventional transport medium tube filled with 3 ml of medium results a 5 fold increase in concentration of the collected sample. Other \u003cem data-mce-fragment=\"1\"\u003eSkinnyTube\u003c\/em\u003e™ 10X Dx™ products with different fill volumes ranging from 0.2-0.6 ml can result in 5-15 X gain in concentration (compared to a conventional fill volume of 3 ml in a conventional tube). \u003c\/span\u003e\u003c\/p\u003e\n\u003cspan data-mce-fragment=\"1\"\u003e \u003c\/span\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003eT\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\" data-ccp-parastyle=\"Normal (Web)\"\u003ehe ready-to-use system combines \u003c\/span\u003e\u003cspan data-mce-fragment=\"1\" data-ccp-parastyle=\"Normal (Web)\"\u003ea\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\" data-ccp-parastyle=\"Normal (Web)\"\u003e disposable \u003c\/span\u003e\u003cspan data-mce-fragment=\"1\" data-contrast=\"auto\" style=\"font-size: 0.875rem;\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003cem data-mce-fragment=\"1\"\u003eSkinnyTube\u003c\/em\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\" data-contrast=\"auto\" style=\"font-size: 0.875rem;\"\u003e™ transport tube filled with non-inactivating viral transport medium (VTM) and a Puritan® PurFlock Ultra® Flocked Sterile nasal swab for efficient collection and safe transport. Each kit contains 1 SkinnyTube™ 5X Dx™ screw-cap cylindrical contour tube filled with 0.6 ml VTM and 1 Puritan® PurFlock Ultra® Sterile Flocked Nasal Swab. The VTM is stable from 2\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\" data-contrast=\"none\" style=\"font-size: 0.875rem;\"\u003e°C to 4\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\" data-contrast=\"none\" style=\"font-size: 0.875rem;\"\u003e°C with a neutral pH maintained by a buffer solution comprised of antimicrobial agents in addition to sources of protein and sucrose to support virus preservation for up to 48 hours. \u003c\/span\u003e\u003cspan data-mce-fragment=\"1\" data-ccp-props='{\"134233117\":true,\"134233118\":true,\"335551550\":6,\"335551620\":6}' style=\"font-size: 0.875rem;\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eThe non-inactivating viral transport medium included in these products is a universal transport medium formulated for virus preservation (Table 1). The key ingredients include:   \u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cem data-mce-fragment=\"1\"\u003eTable 1: Transport Medium Composition\u003c\/em\u003e \u003c\/p\u003e\n\u003ctable data-mce-fragment=\"1\" width=\"0\"\u003e\n\u003ctbody data-mce-fragment=\"1\"\u003e\n\u003ctr data-mce-fragment=\"1\"\u003e\n\u003ctd data-mce-fragment=\"1\" width=\"233\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eHank’s Balanced Salts \u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd data-mce-fragment=\"1\" width=\"233\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eL-Glutamic Acid \u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\"\u003e\n\u003ctd data-mce-fragment=\"1\" width=\"233\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eBovine Serum Albumin \u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd data-mce-fragment=\"1\" width=\"233\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003ePhenol Red \u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\"\u003e\n\u003ctd data-mce-fragment=\"1\" width=\"233\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eGelatin \u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd data-mce-fragment=\"1\" width=\"233\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eColistin \u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\"\u003e\n\u003ctd data-mce-fragment=\"1\" width=\"233\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eSucrose \u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd data-mce-fragment=\"1\" width=\"233\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eAmphotericin B \u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\"\u003e\n\u003ctd data-mce-fragment=\"1\" width=\"233\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eL-Cysteine \u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd data-mce-fragment=\"1\" width=\"233\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eVancomycin \u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr data-mce-fragment=\"1\"\u003e\n\u003ctd data-mce-fragment=\"1\" width=\"233\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eHEPES \u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd data-mce-fragment=\"1\" width=\"233\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003epH: 7.3 ± 0.2 \u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp data-mce-fragment=\"1\"\u003e \u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" data-contrast=\"none\"\u003ePROCEDURE \u003c\/span\u003e\u003cspan data-mce-fragment=\"1\" data-contrast=\"auto\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003col data-mce-fragment=\"1\"\u003e\n\u003cli data-mce-fragment=\"1\"\u003e\n\u003cspan data-mce-fragment=\"1\" data-contrast=\"auto\"\u003e Open package containing the Puritan® swab and SkinnyTube™ tube filled with VTM.\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\" data-ccp-props='{\"335551550\":6,\"335551620\":6}'\u003e\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003e\n\u003cspan data-mce-fragment=\"1\" data-contrast=\"auto\"\u003e Open the sterile swab pouch and collect the specimen without bending the nasal swab as directed by Puritan®. \u003c\/span\u003e\u003cspan data-mce-fragment=\"1\" data-ccp-props='{\"335551550\":6,\"335551620\":6}'\u003e\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003e\n\u003cspan data-mce-fragment=\"1\" data-contrast=\"auto\"\u003e Unscrew the tube’s cap aseptically and insert swab containing the sample into the media in the inner compartment without touching any other surfaces to prevent contamination.\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\" data-ccp-props='{\"335551550\":6,\"335551620\":6}'\u003e\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003e\n\u003cspan data-mce-fragment=\"1\" data-contrast=\"auto\"\u003e Snap swab at the breakpoint highlighted by the black line using the edge of the tube and appropriately discard of the upper portion of the used swab into a medical waste container. \u003c\/span\u003e\u003cspan data-mce-fragment=\"1\" data-ccp-props='{\"335551550\":6,\"335551620\":6}'\u003e\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003e\n\u003cspan data-mce-fragment=\"1\" data-contrast=\"auto\"\u003e Align and lower the plunger with the opening of the inner compartment to seal off the medium tube and screw the cap back on to properly seal the tube. \u003c\/span\u003e\u003cspan data-mce-fragment=\"1\" data-ccp-props='{\"335551550\":6,\"335551620\":6}'\u003e\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003e\n\u003cspan data-mce-fragment=\"1\" data-contrast=\"auto\"\u003e Label the tube containing the specimen using appropriate identifications. \u003c\/span\u003e\u003cspan data-mce-fragment=\"1\" data-ccp-props='{\"335551550\":6,\"335551620\":6}'\u003e\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003e\n\u003cspan data-mce-fragment=\"1\" data-contrast=\"auto\"\u003e Follow local institutional procedures and send the SkinnyTube™ tube sample to the laboratory for analysis. \u003c\/span\u003e\u003cspan data-mce-fragment=\"1\" data-ccp-props='{\"335551550\":6,\"335551620\":6}'\u003e\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e \u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eSPECIFICATIONS\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eDesigned for compatibility with the Puritan® PurFlock Ultra® Sterile Flocked Nasal Swab with a break point at 30 mm.  \u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eDimensions:    Tube: 9.0 cm (height) by 5.5 cm (circumference) \u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eSwab: 153.4 mm handle (length) with 3.429 mm tip (diameter).\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eMaterials:       Tube: Polypropylene tube, silicone inner cap, and high-density polyethylene plastic (HDPE) cap (red) \u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eSwab: Polystyrene handle and flocked polyester tip. \u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e \u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003ePERFORMANCE CHARACTERISTICS\u003c\/strong\u003e\u003c\/span\u003e\u003cspan data-mce-fragment=\"1\" data-ccp-props='{\"201341983\":0,\"335559740\":259}'\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" data-contrast=\"auto\"\u003eTo investigate on the notion of raised analyte concentration in the novel tube compared to that of the conventional tube, the SkinnyTube™ with 0.3 ml of Hanks-balanced salt-based medium was compared to the conventional tube with 3 ml of Hanks-balanced salt based medium. \u003c\/span\u003e\u003cspan data-mce-fragment=\"1\" data-ccp-props='{\"201341983\":0,\"335559740\":259}'\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" data-contrast=\"auto\"\u003eA total of 36 swabs were tested. Each of the 36 swabs was dipped into a spiked mock sample containing a SARS-CoV-2 RNA (COVID-19 viral RNA). Then each of 18 dipped swabs was placed into a separate SkinnyTube™ (novel tube); each of the other 18 swabs were placed into a separate conventional tube. 100uL of the transport medium from each of the 36 tubes was removed, heated, and then tested in a duplex SARS-CoV-2 quantitative reverse transcription polymerase chain reaction (RT-qPCR). \u003c\/span\u003e\u003cspan data-mce-fragment=\"1\" data-ccp-props='{\"201341983\":0,\"335559740\":259}'\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" data-contrast=\"auto\"\u003eA duplex SARS-CoV-2 RT-qPCR tested 2 regions (N1 and N2 regions of the N gene) of the viral SARS-CoV-2 RNA to further validate the assay results. The cycle threshold (Ct) values from the RT-qPCR are listed below in Figure 1. The results showed that the average Ct value for N1 Region for the novel tube was 29.6 or was 3.1 less than that for the conventional tube (average Ct 32.7). Since Ct is a direct reflection of the analyte concentration, this difference corresponds to 8.5-fold more viral RNA analyte concentration in the novel tube than that for the conventional tube. The difference of average Ct value for N2 Region between the two groups of tubes was 4.7 (average Ct 35.5-30.9), corresponding to 25-fold viral RNA analyte concentration in the novel tube than that for the conventional tube. This \u0026gt; 10-fold increase in the viral RNA analyte concentration for N2 test was probably because when the assay result was near 37, the errors in Ct were inherently greater. \u003c\/span\u003e\u003cspan data-mce-fragment=\"1\" data-ccp-props='{\"201341983\":0,\"335559740\":259}'\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\" data-contrast=\"auto\"\u003eThe N2 Region assay data showed that 5 of 18 (28%) samples were not even detectable (Ct\u0026lt;45 or 43 as criterion) in the conventional tube group, whereas all 18 samples in the novel tubes were detected. This suggests that the novel tubes are particularly more useful in the detection of low concentration (low positives near cut-off of an assay) samples .\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e For more information, please visit: \u003cstrong\u003e\u003ca href=\"http:\/\/www.skinnytube.ca\" title=\"skinnytube.ca\"\u003eskinnytube.ca\u003c\/a\u003e. For research use only\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e","brand":"GeneBio Systems","offers":[{"title":"50 Kits","offer_id":42356242153572,"sku":"SKT-031A-01","price":301.8,"currency_code":"CAD","in_stock":true},{"title":"300 Kits","offer_id":42356242186340,"sku":"SKT-031A-02","price":1632.96,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/files\/skinnytubekitimage_8af13f35-bbcb-436f-9a4e-964a0ee4f475.png?v=1699043526"}],"url":"https:\/\/www.genebiosystems.com\/collections\/skinnytube-10x-dx.oembed","provider":"GeneBio ","version":"1.0","type":"link"}